DRV2605: the settings of the registers 0x16, 0x17, 0x1A

May I ask whether the settings of the registers 0x16, 0x17, 0x1A are mainly determined the last settings, or is it recommended to determined in the Auto-Calibration stage?
1. Will the settings set in the Initialization stage be overwritten by Auto-Calibration?
2. Will Auto-Calibration settings affect the results of 0x18, 0x19, 0x1A?
3. After Auto-Calibration, if you set 0x16, 0x17, 0x1A again, is it valid?